Found 7 matching trials
A Phase 1/2 Study of Intravenous Gene Transfer With an AAV9 Vector Expressing Human Beta-galactosidase in Type I and Type II GM1 Gangliosidosis
PHASE1Background:
GM1 gangliosidosis is a disorder that destroys nerve cells. It...
Location
National Institutes of Health Clinical Center
Reduced-Intensity Hematopoietic Stem Cell Transplant for High Risk Lysosomal and Peroxisomal Disorders
NAThis study is designed to test the ability to achieve donor hematopoietic e...
Location
Masonic Cancer Center, University of Minnesota
Safety and Efficacy of Adjunctive GM1 to Mechanical Thrombectomy for Acute Anterior Circulation Large Vessel Occlusion
PHASE4Stroke is a leading cause of global mortality and morbidity, with acute isc...
Location
Xuanwu Hospital, Capital Medical University.
Prenatal Intravenous Gene Transfer With an AAV9 Vector Expressing Human Beta-galactosidase in Type I and Type II GM1 Gangliosidosis Clinical Trial
PHASE1This is a study for the administration of in utero AAV9 transfer in prenata...
Location
Multiple Locations
Effect of GM1 in Prevention of Taxanes Induced Neurotoxicity in Operable Breast Cancer
PHASE3Background: Taxane plays a key role in the treatment of breast cancer and t...
Location
Sun Yat-sen University Cancer Center
BMS-986489 (Atigotatug + Nivolumab) vs Durvalumab in Limited-stage Small-cell Lung Cancer (TIGOS-LS)
PHASE2This is an open-label, randomized study of BMS-986489 (atigotatug + nivolum...
Location
Southern Cancer Center
Safety Evaluation of Intravenous Talineuren (TLN) in Parkinson's Disease-affected Patients
PHASE1This study is an open-label, single ascending dose escalation followed by a...
Location
Neurologisches Institut Konolfingen